GBP2 antibody (AA 160-240)

Catalog No. ABIN7228622

The Rabbit Polyclonal anti-GBP2 antibody (ABIN7228622) specifically detects GBP2 in WB and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for GBP2 antibody (AA 160-240) (ABIN7228622)

Target: GBP2 (Guanylate Binding Protein 2, Interferon-Inducible (GBP2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GBP2 Antibody

Binding Specificity: AA 160-240

Purpose: Rabbit Anti-GBP2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of GBP2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human GBP2 protein at AA range: 160-240

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GBP2

Target: GBP2 (Guanylate Binding Protein 2, Interferon-Inducible (GBP2))

Alternative Name: GBP2

Background: Guanylate-binding protein 2, GTP-binding protein 2, GBP-2, HuGBP-2, Guanine nucleotide-binding protein 2, Interferon-induced guanylate-binding protein 2GBP2 belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas. GBP2 (Guanylate Binding Protein 2) is a Protein Coding gene. Among its related pathways are NF-kB (NFkB) Pathway and Interferon gamma signaling. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is GBP1.

Molecular Weight: 65kD

Gene ID: 2634

UniProt: P32456

Pathways: Cellular Response to Molecule of Bacterial Origin