GBP5 antibody (Internal Region)

Catalog No. ABIN7219352

The Rabbit Polyclonal anti-GBP5 antibody (ABIN7219352) specifically detects GBP5 in WB, ELISA, IHC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for GBP5 antibody (Internal Region) (ABIN7219352)

Target: GBP5 (Guanylate Binding Protein 5 (GBP5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBP5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-GBP5 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-GBP5 Polyclonal Antibody

Specificity: GBP5 Polyclonal Antibody detects endogenous levels of GBP5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human GBP5

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GBP5

Target: GBP5 (Guanylate Binding Protein 5 (GBP5))

Alternative Name: GBP5

Background: GBP5, Guanylate-binding protein 5, GBP-TA antigen, GTP-binding protein 5, GBP-5, Guanine nucleotide-binding protein 5GBP5 (Guanylate Binding Protein 5) is a Protein Coding gene. Diseases associated with GBP5 include chronic active epstein-barr virus infection. Among its related pathways are Immune System and Interferon gamma signaling. GO annotations related to this gene include identical protein binding and GTPase activity. An important paralog of this gene is GBP7. s an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, agents (PubMed: 22461501). Hydrolyzes GTP, but in contrast to other family members, does not produce GMP (PubMed: 20180847).

Molecular Weight: 66kD

Gene ID: 115362

UniProt: Q96PP8