H2AFZ antibody (AA 1-30)

Catalog No. ABIN7227046

This anti-H2AFZ antibody is a Rabbit Polyclonal antibody detecting H2AFZ in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for H2AFZ antibody (AA 1-30) (ABIN7227046)

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This H2AFZ antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-H2AFZ Antibody

Binding Specificity: AA 1-30

Purpose: Histone H2A.Z Polyclonal Antibody

Specificity: The antibody detects endogenous Histone H2A.Z.

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthetic peptide from human protein at AA range: 1-30

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for H2AFZ

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Alternative Name: Histone H2A.Z

Background: Rabbit Anti-Histone H2A.Z Polyclonal Antibody,Histone H2A.Z, H2A/z,Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. H2AFZ (H2A histone family member Z) encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.,Histone H2A.Z

Molecular Weight: observerd band 20kDa

Gene ID: 3015

UniProt: P0C0S5

Pathways: Telomere Maintenance