Hemoglobin Subunit beta antibody

Catalog No. ABIN7228854

The Rabbit Polyclonal anti-Hemoglobin Subunit beta antibody (ABIN7228854) specifically detects Hemoglobin Subunit beta in WB and ELISA. The antibody is reactive with Human and Rat samples.

Quick Overview for Hemoglobin Subunit beta antibody (ABIN7228854)

Target: Hemoglobin Subunit beta (HBB) (Hemoglobin beta (HBB))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Hemoglobin Subunit beta antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Hemoglobin Subunit beta Antibody

Purpose: Rabbit Anti-HBB Polyclonal Antibody

Specificity: The antibody detects endogenous levels of HBB protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human HBB protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Hemoglobin Subunit beta

Target: Hemoglobin Subunit beta (HBB) (Hemoglobin beta (HBB))

Alternative Name: HBB

Background: Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chainThe alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Molecular Weight: 16kD

Gene ID: 3043

UniProt: P68871