HBA1 antibody (AA 30-110)

Catalog No. ABIN7228850

This Rabbit Polyclonal antibody specifically detects HBA1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for HBA1 antibody (AA 30-110) (ABIN7228850)

Target: HBA1 (Hemoglobin, alpha 1 (HBA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HBA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HBA1 Antibody

Binding Specificity: AA 30-110

Purpose: Rabbit Anti-HBA Polyclonal Antibody

Specificity: The antibody detects endogenous levels of HBA protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human HBA protein at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HBA1

Target: HBA1 (Hemoglobin, alpha 1 (HBA1))

Alternative Name: HBA

Background: Alpha-globin, Hemoglobin alpha chainThe human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'-zeta-pseudozeta-mu-pseudoalpha-1-alpha-2-alpha-1-theta-3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97 % of the total hemoglobin, alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3 % of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1, some nondeletion alpha thalassemias have also been reported.

Molecular Weight: 15kD

Gene ID: 3039

UniProt: P69905