HDGF antibody (AA 141-190)

Catalog No. ABIN7228874

The Rabbit Polyclonal anti-HDGF antibody (ABIN7228874) specifically detects HDGF in IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for HDGF antibody (AA 141-190) (ABIN7228874)

Target: HDGF (Hepatoma-Derived Growth Factor (HDGF))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDGF antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-HDGF Antibody

Binding Specificity: AA 141-190

Purpose: Rabbit Anti-HDGF Polyclonal Antibody

Specificity: The antibody detects endogenous levels of HDGF

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human HDGF protein at AA range: 141-190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HDGF

Target: HDGF (Hepatoma-Derived Growth Factor (HDGF))

Alternative Name: HDGF

Background: Hepatoma-derived growth factor, HDGF, High mobility group protein 1-like 2, HMG-1L2HDGF encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. High levels of expression of HDGF enhance the growth of many tumors. HDGF was thought initially to be located on chromosome X, however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described. HDGF (Heparin Binding Growth Factor) is a Protein Coding gene. Diseases associated with HDGF include Lung Cancer and Hepatocellular Carcinoma. Among its related pathways are p70S6K Signaling and Akt Signaling.

Gene ID: 3068

UniProt: P51858

Pathways: ER-Nucleus Signaling