HPS5 antibody

Catalog No. ABIN7228964

The Rabbit Polyclonal anti-HPS5 antibody is suitable to detect HPS5 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for HPS5 antibody (ABIN7228964)

Target: HPS5 (Hermansky-Pudlak Syndrome 5 (HPS5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HPS5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HPS5 Antibody

Purpose: Rabbit Anti-HPS5 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of HPS5 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human HPS5 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HPS5

Target: HPS5 (Hermansky-Pudlak Syndrome 5 (HPS5))

Alternative Name: HPS5

Background: Hermansky-Pudlak syndrome 5 protein, Alpha-integrin-binding protein 63, Ruby-eye protein 2 homolog, Ru2HPS5 encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha-3. Mutations in HPS5 are associated with Hermansky-Pudlak syndrome type 5. Multiple transcript variants encoding two distinct isoforms have been identified for HPS5. HPS5 (HPS5, Biogenesis Of Lysosomal Organelles Complex 2 Subunit 2) is a Protein Coding gene. Diseases associated with HPS5 include Hermansky-Pudlak Syndrome 5 and Hermansky-Pudlak Syndrome Without Pulmonary Fibrosis. An important paralog of HPS5 is TECPR2.

Molecular Weight: 124kD

Gene ID: 11234

UniProt: Q9UPZ3