HNRNPAB antibody

Catalog No. ABIN7231118

The Rabbit Polyclonal anti-HNRNPAB antibody is suitable to detect HNRNPAB in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for HNRNPAB antibody (ABIN7231118)

Target: HNRNPAB (Heterogeneous Nuclear Ribonucleoprotein A/B (HNRNPAB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPAB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HNRNPAB Antibody

Purpose: Rabbit Anti-ROAA Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ROAA protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ROAA protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HNRNPAB

Target: HNRNPAB (Heterogeneous Nuclear Ribonucleoprotein A/B (HNRNPAB))

Alternative Name: ROAA

Background: Heterogeneous nuclear ribonucleoprotein A/B, hnRNP A/B, APOBEC1-binding protein 1, ABBP-1HNRNPAB belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molecular Weight: 36kD

Gene ID: 3182

UniProt: Q99729