HNRPDL antibody (AA 210-290)

Catalog No. ABIN7226200

The Rabbit Polyclonal anti-HNRPDL antibody (ABIN7226200) specifically detects HNRPDL in ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for HNRPDL antibody (AA 210-290) (ABIN7226200)

Target: HNRPDL (Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRPDL antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-HNRPDL Antibody

Binding Specificity: AA 210-290

Purpose: Rabbit Anti-hnRNP DL Polyclonal Antibody

Specificity: HnRNP DL Polyclonal Antibody detects endogenous levels of hnRNP DL protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human hnRNP DL at AA range: 210-290

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HNRPDL

Target: HNRPDL (Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL))

Alternative Name: hnRNP DL

Background: HNRPDL, JKTBP, Heterogeneous nuclear ribonucleoprotein D-like, hnRNP D-like, hnRNP DL, AU-rich element RNA-binding factor, JKT41-binding protein, Protein laAUF1HNRNPDL (heterogeneous nuclear ribonucleoprotein D like) belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by HNRNPDL has two RRM domains that bind to RNAs. Three alternatively spliced transcript variants have been described for HNRNPDL. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein isoforms encoded by HNRNPDL are similar to its family member HNRPD.

Gene ID: 9987

UniProt: O14979