HMGN2 antibody (pSer29)

Catalog No. ABIN7221506

The Rabbit Polyclonal anti-HMGN2 antibody (ABIN7221506) specifically detects HMGN2 in IHC, ELISA and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for HMGN2 antibody (pSer29) (ABIN7221506)

Target: HMGN2 (High Mobility Group Nucleosomal Binding Domain 2 (HMGN2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGN2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-HMGN2 Antibody

Binding Specificity: pSer29

Purpose: Rabbit Anti-HMG-17 (phospho Ser29) Polyclonal Antibody

Specificity: Phospho-HMG-17 (S29) Polyclonal Antibody detects endogenous levels of HMG-17 protein only when phosphorylated at S29.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human HMG-17 Phospho-Ser29

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HMGN2

Target: HMGN2 (High Mobility Group Nucleosomal Binding Domain 2 (HMGN2))

Alternative Name: HMG-17

Background: HMGN2, HMG17, Non-histone chromosomal protein HMG-17, High mobility group nucleosome-binding domain-containing protein 2The high mobility group nucleosomal binding domain 2 encoded by HMGN2 binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi.

Molecular Weight: 15-17kD

Gene ID: 3151

UniProt: P05204