HRH4 antibody (AA 190-270)

Catalog No. ABIN7223958

The Rabbit Polyclonal anti-HRH4 antibody is suitable to detect HRH4 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IF.

Quick Overview for HRH4 antibody (AA 190-270) (ABIN7223958)

Target: HRH4 (Histamine Receptor H4 (HRH4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HRH4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-HRH4 Antibody

Binding Specificity: AA 190-270

Purpose: Rabbit Anti-Histamine H4 Receptor Polyclonal Antibody

Specificity: Histamine H4 Receptor Polyclonal Antibody detects endogenous levels of Histamine H4 Receptor protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Histamine H4 Receptor at AA range: 190-270

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HRH4

Target: HRH4 (Histamine Receptor H4 (HRH4))

Alternative Name: Histamine H4 Receptor

Background: HRH4, GPCR105, Histamine H4 receptor, H4R, HH4R, AXOR35, G-protein coupled receptor 105, GPRv53, Pfi-013, SP9144Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. HRH4 (histamine receptor H4) encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for HRH4.

Molecular Weight: 45kD

Gene ID: 59340

UniProt: Q9H3N8