Neuregulin 3 antibody (AA 351-450) (HRP)

Catalog No. ABIN716165

The Rabbit Polyclonal anti-Neuregulin 3 antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect Neuregulin 3 in samples from Rat.

Quick Overview for Neuregulin 3 antibody (AA 351-450) (HRP) (ABIN716165)

Target: Neuregulin 3 (NRG3)

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neuregulin 3 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Neuregulin 3 Antibody (HRP)

Binding Specificity: AA 351-450

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NRG3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Neuregulin 3

Target: Neuregulin 3 (NRG3)

Alternative Name: NRG3

Background:

Synonyms: HRG3, Neuregulin 3, Neuregulin 3 like polypeptide, Neuregulin-3, Neuregulin3, NRG-3, Nrg3, NRG3_HUMAN, pro NRG3, Pro-NRG3.

Background: Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes.

Gene ID: 10718

Pathways: RTK Signaling