HNF-3alpha/beta/gamma antibody

Catalog No. ABIN7218182

This Rabbit Polyclonal antibody specifically detects HNF-3alpha/beta/gamma in ELISA and WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for HNF-3alpha/beta/gamma antibody (ABIN7218182)

Target: HNF-3alpha/beta/gamma

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNF-3alpha/beta/gamma antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-HNF-3alpha/beta/gamma Antibody

Purpose: Rabbit Anti-HNF-3α/β/γ Polyclonal Antibody

Specificity: HNF-3α/β/γ Polyclonal Antibody detects endogenous levels of HNF-3α/β/γ protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human HNF-3alpha/beta/gamma around the non-acetylation site of K265

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HNF-3alpha/beta/gamma

Target: HNF-3alpha/beta/gamma

Background: FOXA1, HNF3A, TCF3A, Hepatocyte nuclear factor 3-alpha, HNF-3-alpha, HNF-3A, Forkhead box protein A1, Transcription factor 3A, TCF-3A, FOXA2, HNF3B, TCF3B, Hepatocyte nuclear factor 3-beta, HNF-3-beta, HNF-3B, Forkhead box protein A2, Transcription factor 3B, TCF-3B, FOXA3, HNF3G, TCF3G, Hepatocyte nuclear factor 3-gamma, HNF-3-gamma, HNF-3G, Fork head-related protein FKH H3, Forkhead box protein A3, Transcription factor 3G, TCF-3GFOXA1 encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver.

Molecular Weight: 50kD

Gene ID: 3169

UniProt: P55317