HJURP antibody (AA 80-160)

Catalog No. ABIN7228926

This Rabbit Polyclonal antibody specifically detects HJURP in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for HJURP antibody (AA 80-160) (ABIN7228926)

Target: HJURP (Holliday Junction Recognition Protein (HJURP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HJURP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HJURP Antibody

Binding Specificity: AA 80-160

Purpose: HJURP Polyclonal Antibody

Specificity: The antibody detects endogenous levels of HJURP protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human HJURP protein at AA range: 80-160

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for HJURP

Target: HJURP (Holliday Junction Recognition Protein (HJURP))

Alternative Name: HJURP

Background: Rabbit Anti-HJURP Polyclonal Antibody,Holliday junction recognition protein, 14-3-3-associated AKT substrate, Fetal liver-expressing gene 1 protein, Up-regulated in lung cancer 9,HJURP (Holliday Junction Recognition Protein) is a Protein Coding gene. Diseases associated with HJURP include Fibrillary Astrocytoma. Among its related pathways are DNA Damage and Chromosome Maintenance. Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions.,HJURP

Molecular Weight: observerd band 82kDa

Gene ID: 55355

UniProt: Q8NCD3