HJURP antibody (AA 650-700)

Catalog No. ABIN7453582

Product Details anti-HJURP Antibody

Target: HJURP (Holliday Junction Recognition Protein (HJURP))

Binding Specificity: AA 650-700

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HJURP antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-HJURP Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 650 and 700

Isotype: IgG

Application Details

Application Notes:

IHC: 1:1,000 to 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for HJURP

Target: HJURP (Holliday Junction Recognition Protein (HJURP))

Alternative Name: HJURP (HJURP Products)

Synonyms: Gm975 antibody, Mfleg1 antibody, MGC66590 antibody, C330011F01Rik antibody, FAKTS antibody, URLC9 antibody, hFLEG1 antibody, Holliday junction recognition protein antibody, Hjurp antibody, HJURP antibody

Background: Background: Holliday junction recognition protein (HJURP) is a centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. HJURP acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. HJURP directly binds Holliday junctions [taken from the Universal Protein Resource (UniProt) Q8NCD3].

Gene ID: 55355

NCBI Accession: NP_060880

UniProt: Q8NCD3