HOXD10 antibody (AA 260-340)

Catalog No. ABIN7221550

The Rabbit Polyclonal anti-HOXD10 antibody (ABIN7221550) specifically detects HOXD10 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for HOXD10 antibody (AA 260-340) (ABIN7221550)

Target: HOXD10 (Homeobox D10 (HOXD10))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXD10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HOXD10 Antibody

Binding Specificity: AA 260-340

Purpose: Rabbit Anti-HoxD10 Polyclonal Antibody

Specificity: HoxD10 Polyclonal Antibody detects endogenous levels of HoxD10 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human HoxD10 at AA range: 260-340

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HOXD10

Target: HOXD10 (Homeobox D10 (HOXD10))

Alternative Name: HoxD10

Background: HOXD10, HOX4D, HOX4E, Homeobox protein Hox-D10, Homeobox protein Hox-4D, Homeobox protein Hox-4EHOXD10 is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The homeobox D10 functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.

Molecular Weight: 32kD

Gene ID: 3236

UniProt: P28358