HOXD3 antibody (Internal Region)

Catalog No. ABIN7217928

The Rabbit Polyclonal anti-HOXD3 antibody is suitable to detect HOXD3 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IF and IHC.

Quick Overview for HOXD3 antibody (Internal Region) (ABIN7217928)

Target: HOXD3 (Homeobox D3 (HOXD3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXD3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-HOXD3 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-HoxD3 Polyclonal Antibody

Specificity: HoxD3 Polyclonal Antibody detects endogenous levels of HoxD3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human HoxD3

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HOXD3

Target: HOXD3 (Homeobox D3 (HOXD3))

Alternative Name: HoxD3

Background: HOXD3, HOX1D, HOX4A, Homeobox protein Hox-D3, Homeobox protein Hox-4AHOXD3 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. Homeobox protein Hox-D3 encoded by this gene may play a role in the regulation of cell adhesion processes.

Molecular Weight: 45kD

Gene ID: 3232

UniProt: P31249