HOXD8 antibody (AA 210-290)

Catalog No. ABIN7221548

The Rabbit Polyclonal anti-HOXD8 antibody (ABIN7221548) specifically detects HOXD8 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for HOXD8 antibody (AA 210-290) (ABIN7221548)

Target: HOXD8 (Homeobox D8 (HOXD8))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXD8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HOXD8 Antibody

Binding Specificity: AA 210-290

Purpose: Rabbit Anti-HoxD8 Polyclonal Antibody

Specificity: HoxD8 Polyclonal Antibody detects endogenous levels of HoxD8 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human HoxD8 at AA range: 210-290

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HOXD8

Target: HOXD8 (Homeobox D8 (HOXD8))

Alternative Name: HoxD8

Background: HOXD8, HOX4E, Homeobox protein Hox-D8, Homeobox protein Hox-4E, Homeobox protein Hox-5.4HOXD8 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. HOXD8 is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function. Alternate splicing results in multiple transcript variants.

Molecular Weight: 32kD

Gene ID: 3234

UniProt: P13378