HMCS1 antibody

Catalog No. ABIN7228936

The Rabbit Polyclonal anti-HMCS1 antibody is suitable to detect HMCS1 in samples from Human, Mouse and Rat. It has been validated for ELISA and WB.

Quick Overview for HMCS1 antibody (ABIN7228936)

Target: HMCS1 (Hydroxymethylglutaryl-Coa Synthase (HMCS1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMCS1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-HMCS1 Antibody

Purpose: Rabbit Anti-HMCS1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of HMCS1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human HMCS1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HMCS1

Target: HMCS1 (Hydroxymethylglutaryl-Coa Synthase (HMCS1))

Alternative Name: HMCS1

Background: Hydroxymethylglutaryl-CoA synthase, cytoplasmic, HMG-CoA synthase, 3-hydroxy-3-methylglutaryl coenzyme A synthaseThis enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. HMGCS1 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 1) is a Protein Coding gene. Among its related pathways are Terpenoid backbone biosynthesis and Metabolism. GO annotations related to HMGCS1 include protein homodimerization activity and isomerase activity. An important paralog of HMGCS1e is HMGCS2.

Molecular Weight: 57kD

Gene ID: 3157

UniProt: Q01581