HSD17B12 antibody

Catalog No. ABIN7228200

The Rabbit Polyclonal anti-HSD17B12 antibody is suitable to detect HSD17B12 in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for HSD17B12 antibody (ABIN7228200)

Target: HSD17B12 (Hydroxysteroid (17-Beta) Dehydrogenase 12 (HSD17B12))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD17B12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HSD17B12 Antibody

Purpose: Rabbit Anti-DHB12 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of DHB12 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human DHB12 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HSD17B12

Target: HSD17B12 (Hydroxysteroid (17-Beta) Dehydrogenase 12 (HSD17B12))

Alternative Name: DHB12

Background: Very-long-chain 3-oxoacyl-CoA reductase, 17-beta-hydroxysteroid dehydrogenase 12, 17-beta-HSD 12, 3-ketoacyl-CoA reductase, KAR, Estradiol 17-beta-dehydrogenase 12, Short chain dehydrogenase/reductase family 12C member 1HSD17B12 encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. HSD17B12 (Hydroxysteroid 17-Beta Dehydrogenase 12) is a Protein Coding gene. Among its related pathways are Fatty acid elongation and Metabolism.

Molecular Weight: 34kD

Gene ID: 51144

UniProt: Q53GQ0

Pathways: Steroid Hormone Biosynthesis