HSD17B2 antibody

Catalog No. ABIN7228204

The Rabbit Polyclonal anti-HSD17B2 antibody (ABIN7228204) specifically detects HSD17B2 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for HSD17B2 antibody (ABIN7228204)

Target: HSD17B2 (Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD17B2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HSD17B2 Antibody

Purpose: Rabbit Anti-DHB2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of DHB2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human DHB2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HSD17B2

Target: HSD17B2 (Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2))

Alternative Name: DHB2

Background: Estradiol 17-beta-dehydrogenase 2, 17-beta-hydroxysteroid dehydrogenase type 2, 17-beta-HSD 2, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, E2DH, Microsomal 17-beta-hydroxysteroid dehydrogenase, Short chain dehydrogenase/reductase family 9C member 2, Testosterone 17-beta-dehydrogenaseHSD17B2 (Hydroxysteroid 17-Beta Dehydrogenase 2) is a Protein Coding gene. Diseases associated with HSD17B2 include Progesterone Resistance and Endometriosis Of Ovary. Among its related pathways are Ovarian steroidogenesis and Metabolism. HSD17B2 is capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. HSD17B2 also has 20-alpha-HSD activity. HSD17B2 uses NADH while EDH17B3 uses NADPH.

Molecular Weight: 42kD

Gene ID: 3294

UniProt: P37059

Pathways: Steroid Hormone Biosynthesis