HCRTR2 antibody (AA 210-290)

Catalog No. ABIN7216338

The Rabbit Polyclonal anti-HCRTR2 antibody (ABIN7216338) specifically detects HCRTR2 in ELISA and WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for HCRTR2 antibody (AA 210-290) (ABIN7216338)

Target: HCRTR2 (Hypocretin (Orexin) Receptor 2 (HCRTR2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HCRTR2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-HCRTR2 Antibody

Binding Specificity: AA 210-290

Purpose: Rabbit Anti-OX2R Polyclonal Antibody

Specificity: OX2R Polyclonal Antibody detects endogenous levels of OX2R protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human OX2R at AA range: 210-290

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HCRTR2

Target: HCRTR2 (Hypocretin (Orexin) Receptor 2 (HCRTR2))

Alternative Name: OX2R

Background: CD200R1, CD200R, CRTR2, MOX2R, OX2R, Cell surface glycoprotein CD200 receptor 1, CD200 cell surface glycoprotein receptor, Cell surface glycoprotein OX2 receptor 1CD200R1 encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. Alternative splicing of CD200R1 results in multiple transcript variants.

Molecular Weight: 37kD

Gene ID: 131450

UniProt: Q8TD46

Pathways: Feeding Behaviour