IDS antibody

Catalog No. ABIN7229018

The Rabbit Polyclonal anti-IDS antibody is suitable to detect IDS in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for IDS antibody (ABIN7229018)

Target: IDS (Iduronate 2-Sulfatase (IDS))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IDS antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IDS Antibody

Purpose: Rabbit Anti-IDS Polyclonal Antibody

Specificity: The antibody detects endogenous levels of IDS protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human IDS protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IDS

Target: IDS (Iduronate 2-Sulfatase (IDS))

Alternative Name: IDS

Background: Iduronate 2-sulfatase, Alpha-L-iduronate sulfate sulfatase, IdursulfaseIDS encodes a member of the sulfatase family of proteins. Iduronate 2-Sulfatase is proteolytically processed to generate two polypeptide chains. This enzyme is involved in the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this gene are associated with the X-linked lysosomal storage disease mucopolysaccharidosis type II, also known as Hunter syndrome. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.

Molecular Weight: 60kD

Gene ID: 3423

UniProt: P22304

Pathways: Glycosaminoglycan Metabolic Process