IDUA antibody

Catalog No. ABIN7229020

The Rabbit Polyclonal anti-IDUA antibody (ABIN7229020) specifically detects IDUA in ELISA and WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for IDUA antibody (ABIN7229020)

Target: IDUA (Iduronidase, alpha-L- (IDUA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IDUA antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-IDUA Antibody

Purpose: Rabbit Anti-IDUA Polyclonal Antibody

Specificity: The antibody detects endogenous levels of IDUA protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human IDUA protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IDUA

Target: IDUA (Iduronidase, alpha-L- (IDUA))

Alternative Name: IDUA

Background: Alpha-L-iduronidaseIDUA encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I).

Molecular Weight: 71kD

Gene ID: 3425

UniProt: P35475

Pathways: Glycosaminoglycan Metabolic Process