IKZF2 antibody (AA 300-380)

Catalog No. ABIN7220542

The Rabbit Polyclonal anti-IKZF2 antibody (ABIN7220542) specifically detects IKZF2 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for IKZF2 antibody (AA 300-380) (ABIN7220542)

Target: IKZF2 (IKAROS Family Zinc Finger 2 (IKZF2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IKZF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IKZF2 Antibody

Binding Specificity: AA 300-380

Purpose: Rabbit Anti-Helios Polyclonal Antibody

Specificity: Helios Polyclonal Antibody detects endogenous levels of Helios protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Helios at AA range: 300-380

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IKZF2

Target: IKZF2 (IKAROS Family Zinc Finger 2 (IKZF2))

Alternative Name: Helios

Background: IKZF2, HELIOS, ZNFN1A2, Zinc finger protein Helios, Ikaros family zinc finger protein 2IKZF2 encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.

Molecular Weight: 56kD

Gene ID: 22807

UniProt: Q9UKS7