IGLL1 antibody (N-Term)

Catalog No. ABIN7214048

The Rabbit Polyclonal anti-IGLL1 antibody (ABIN7214048) specifically detects IGLL1 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for IGLL1 antibody (N-Term) (ABIN7214048)

Target: IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGLL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IGLL1 Antibody

Binding Specificity: N-Term

Purpose: Rabbit Anti-CD179b Polyclonal Antibody

Specificity: CD179b Polyclonal Antibody detects endogenous levels of CD179b protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human CD179b

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IGLL1

Target: IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))

Alternative Name: CD179b

Background: IGLL1, IGL1, Immunoglobulin lambda-like polypeptide 1, CD179 antigen-like family member B, Ig lambda-5, Immunoglobulin omega polypeptide, Immunoglobulin-related protein 14.1, CD antigen CD179b, IGLC1, Ig lambda-1 chain C regions, IGLC2, IgThe preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. IGLL1 does not undergo rearrangement. Mutations in IGLL1 can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for IGLL1.

Molecular Weight: 23kD

Gene ID: 3543

UniProt: P15814, P0CG04, P0CG05, P0CG06, P0CF74, A0M8Q6

Pathways: Regulation of Cell Size