Indian Hedgehog antibody (Internal Region)

Catalog No. ABIN7217598

This Rabbit Polyclonal antibody specifically detects Indian Hedgehog in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Indian Hedgehog antibody (Internal Region) (ABIN7217598)

Target: Indian Hedgehog (IHH)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Indian Hedgehog antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Indian Hedgehog Antibody

Binding Specificity: Internal Region

Purpose: Ihh Polyclonal Antibody

Specificity: Ihh Polyclonal Antibody detects endogenous levels of Ihh protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Ihh

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Indian Hedgehog

Target: Indian Hedgehog (IHH)

Alternative Name: Ihh

Background: Rabbit Anti-Ihh Polyclonal Antibody,IHH, Indian hedgehog protein, IHH, HHG-2,IHH encodes a member of the hedgehog family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including an N-terminal fragment that is involved in signaling. Hedgehog family proteins are essential secreted signaling molecules that regulate a variety of developmental processes including growth, patterning and morphogenesis. Indian hedgehog protein encoded by this gene specifically plays a role in bone growth and differentiation. Mutations in this gene are the cause of brachydactyly type A1, which is characterized by shortening or malformation of the fingers and toes. Mutations in this gene are also the cause of acrocapitofemoral dysplasia.,Indian hedgehog protein

Molecular Weight: observerd band 45kDa

Gene ID: 3549

UniProt: Q14623

Pathways: Hedgehog Signaling