ING1 antibody

Catalog No. ABIN7229138

This Rabbit Polyclonal antibody specifically detects ING1 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for ING1 antibody (ABIN7229138)

Target: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ING1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ING1 Antibody

Purpose: Rabbit Anti-ING1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ING1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ING1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ING1

Target: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Alternative Name: ING1

Background: Inhibitor of growth protein 1ING1 encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. Inhibitor Of Growth Family Member 1 is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

Molecular Weight: 46kD

Gene ID: 3621

UniProt: Q9UK53

Pathways: Protein targeting to Nucleus, Autophagy