ING2 antibody

Catalog No. ABIN7229140

The Rabbit Polyclonal anti-ING2 antibody is suitable to detect ING2 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for ING2 antibody (ABIN7229140)

Target: ING2 (Inhibitor of Growth Family, Member 2 (ING2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ING2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ING2 Antibody

Purpose: Rabbit Anti-ING2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ING2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ING2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ING2

Target: ING2 (Inhibitor of Growth Family, Member 2 (ING2))

Alternative Name: ING2

Background: Inhibitor of growth protein 2, Inhibitor of growth 1-like protein, ING1Lp, p32, p33ING2ING2 is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis. Alternative splicing results in multiple transcript variants.

Molecular Weight: 30kD

Gene ID: 3622

UniProt: Q9H160

Pathways: Chromatin Binding, Autophagy, Negative Regulation of intrinsic apoptotic Signaling