INSL3 antibody (AA 10-50)

Catalog No. ABIN7229150

The Rabbit Polyclonal anti-INSL3 antibody is suitable to detect INSL3 in samples from Human, Rat and Mouse. It has been validated for ELISA, IHC and IF.

Quick Overview for INSL3 antibody (AA 10-50) (ABIN7229150)

Target: INSL3 (Insulin-Like 3 (Leydig Cell) (INSL3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INSL3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-INSL3 Antibody

Binding Specificity: AA 10-50

Purpose: Rabbit Anti-INSL3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of INSL3

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human INSL3 protein at AA range: 10-50

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for INSL3

Target: INSL3 (Insulin-Like 3 (Leydig Cell) (INSL3))

Alternative Name: INSL3

Background: Insulin-like 3, Leydig insulin-like peptide, Ley-I-L, Relaxin-like factorINSL3 encodes a member of the insulin-like hormone superfamily. The encoded protein is mainly produced in gonadal tissues. Studies of the mouse counterpart suggest that INSL3 may be involved in the development of urogenital tract and female fertility. This protein may also act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent. Mutations in INSL3 may lead to cryptorchidism. Alternate splicing results in multiple transcript variants. INSL3 (Insulin Like 3) is a Protein Coding gene. Diseases associated with INSL3 include Cryptorchidism and Testicular Cancer. Among its related pathways are G alpha(s) signalling events and Signaling by GPCR.

Gene ID: 3640

UniProt: P51460

Pathways: Hormone Activity, cAMP Metabolic Process