ITGAD antibody (Internal Region)

Catalog No. ABIN7218440

This Rabbit Polyclonal antibody specifically detects ITGAD in WB, IHC, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ITGAD antibody (Internal Region) (ABIN7218440)

Target: ITGAD (Integrin alpha D (ITGAD))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGAD antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-ITGAD Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-Integrin αD Polyclonal Antibody

Specificity: Integrin αD Polyclonal Antibody detects endogenous levels of Integrin αD protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Integrin alphaD

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ITGAD

Target: ITGAD (Integrin alpha D (ITGAD))

Alternative Name: Integrin alphaD

Background: ITGAD, Integrin alpha-D, ADB2, CD11 antigen-like family member D, Leukointegrin alpha D, CD11dITGAD belongs to the beta-2 integrin family of membrane glycoproteins, which are are composed of non-covalently linked alpha and beta subunits to form a heterodimer. It encodes the alpha subunit of the cell surface heterodimers and is involved in the activation and adhesion functions of leukocytes. The gene is located about 11kb downstream of the integrin subunit alpha X gene, another member of the integrin family. It is expressed in the tissue and circulating myeloid leukocytes. Alternative splicing results in multiple transcript variants.

Molecular Weight: 127kD

Gene ID: 3681

UniProt: Q13349

Pathways: Activated T Cell Proliferation, Integrin Complex