ITIH2 antibody (Cleaved-Asp702)

Catalog No. ABIN7212528

The Rabbit Polyclonal anti-ITIH2 antibody is suitable to detect ITIH2 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for ITIH2 antibody (Cleaved-Asp702) (ABIN7212528)

Target: ITIH2 (Inter-alpha Globulin Inhibitor H2 Polypeptide (ITIH2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITIH2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ITIH2 Antibody

Binding Specificity: AA 630-710, Cleaved-Asp702

Purpose: Rabbit Anti-Cleaved-ITI-H2 (D702) Polyclonal Antibody

Specificity: Cleaved-ITI-H2 (D702) Polyclonal Antibody detects endogenous levels of fragment of activated ITI-H2 protein resulting from cleavage adjacent to D702.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human ITI-H2 at AA range: 630-710

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ITIH2

Target: ITIH2 (Inter-alpha Globulin Inhibitor H2 Polypeptide (ITIH2))

Alternative Name: ITI-H2

Background: ITIH2, IGHEP2, Inter-alpha-trypsin inhibitor heavy chain H2, ITI heavy chain H2, ITI-HC2, Inter-alpha-inhibitor heavy chain 2, Inter-alpha-trypsin inhibitor complex component II, Serum-derived hyaluronan-associated protein, SHAPThe inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis. The ITI family contains multiple proteins made up of a light chain (see MIM 176870) and a variable number of heavy chains (Salier et al., 1987 [PubMed 2446322], Himmelfarb et al., 2004 [PubMed 14744536]).[supplied by OMIM, Nov 2009]

Molecular Weight: 72kD

Gene ID: 3698

UniProt: P19823

Pathways: Glycosaminoglycan Metabolic Process