ICAM1 antibody (pTyr512)

Catalog No. ABIN7212998

This Rabbit Polyclonal antibody specifically detects ICAM1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for ICAM1 antibody (pTyr512) (ABIN7212998)

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICAM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ICAM1 Antibody

Binding Specificity: pTyr512

Purpose: ICAM-1 (phospho Tyr512) Polyclonal Antibody

Specificity: Phospho-ICAM-1 (Y512) Polyclonal Antibody detects endogenous levels of ICAM-1 protein only when phosphorylated at Y512.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human ICAM-1 Phospho-Tyr512

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for ICAM1

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Alternative Name: ICAM-1

Background: Rabbit Anti-ICAM-1 (phospho Tyr512) Polyclonal Antibody,ICAM1, Intercellular adhesion molecule 1, ICAM-1, Major group rhinovirus receptor, CD antigen CD54,ICAM1 encodes a cell surface glycoprotein (intercellular adhesion molecule 1) which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b/CD18 and is also exploited by Rhinovirus as a receptor.,Intercellular adhesion molecule 1

Molecular Weight: observerd band 57kDa

Gene ID: 3383

UniProt: P05362

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling