ICAM4 antibody (AA 141-190)

Catalog No. ABIN7227718

The Rabbit Polyclonal anti-ICAM4 antibody is suitable to detect ICAM4 in samples from Human and Mouse. It has been validated for IHC, ELISA and IF.

Quick Overview for ICAM4 antibody (AA 141-190) (ABIN7227718)

Target: ICAM4 (Intercellular Adhesion Molecule 4 (ICAM4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICAM4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-ICAM4 Antibody

Binding Specificity: AA 141-190

Purpose: Rabbit Anti-CD242 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CD242

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CD242 protein at AA range: 141-190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ICAM4

Target: ICAM4 (Intercellular Adhesion Molecule 4 (ICAM4))

Alternative Name: CD242

Background: Intercellular adhesion molecule 4, ICAM-4, Landsteiner-Wiener blood group glycoprotein, LW blood group protein, CD antigen CD242ICAM4 encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100, Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene ID: 3386

UniProt: Q14773