IFRD1 antibody (AA 280-360)

Catalog No. ABIN7229066

This Rabbit Polyclonal antibody specifically detects IFRD1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for IFRD1 antibody (AA 280-360) (ABIN7229066)

Target: IFRD1 (Interferon Related Developmental Regulator 1 (IFRD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFRD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IFRD1 Antibody

Binding Specificity: AA 280-360

Purpose: Rabbit Anti-IFRD1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of IFRD1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human IFRD1 protein at AA range: 280-360

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IFRD1

Target: IFRD1 (Interferon Related Developmental Regulator 1 (IFRD1))

Alternative Name: IFRD1

Background: Interferon-related developmental regulator 1, Nerve growth factor-inducible protein PC4IFRD1 (Interferon Related Developmental Regulator 1) is an immediate early gene that encodes a protein related to interferon-gamma. This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. Mutations in IFRD1 are associated with sensory/motor neuropathy with ataxia. IFRD1 may also be involved in modulating the pathogenesis of cystic fibrosis lung disease. Alternate splicing results in multiple transcript variants. IFRD1 is a Protein Coding gene. Diseases associated with IFRD1 include Spinocerebellar Ataxia 18 and Cystic Fibrosis. Among its related pathways are Hypertrophy Model.

Molecular Weight: 49kD

Gene ID: 3475

UniProt: O00458