IFITM1 antibody (N-Term)

Catalog No. ABIN7218476

The Rabbit Polyclonal anti-IFITM1 antibody is suitable to detect IFITM1 in samples from Human and Mouse. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for IFITM1 antibody (N-Term) (ABIN7218476)

Target: IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFITM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-IFITM1 Antibody

Binding Specificity: N-Term

Purpose: Rabbit Anti-CD225 Polyclonal Antibody

Specificity: CD225 Polyclonal Antibody detects endogenous levels of CD225 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human CD225

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IFITM1

Target: IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))

Alternative Name: CD225

Background: IFITM1, CD225, IFI17, Interferon-induced transmembrane protein 1, Dispanin subfamily A member 2a, DSPA2a, Interferon-induced protein 17, Interferon-inducible protein 9-27, Leu-13 antigen, CD225IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activition or by arresting cell growth in G1 phase in a p53-dependent manner. Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals.

Molecular Weight: 15kD

Gene ID: 8519

UniProt: P13164