IL1RAPL2 antibody (Internal Region)

Catalog No. ABIN7218464

The Rabbit Polyclonal anti-IL1RAPL2 antibody is suitable to detect IL1RAPL2 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for IL1RAPL2 antibody (Internal Region) (ABIN7218464)

Target: IL1RAPL2 (Interleukin 1 Receptor Accessory Protein-Like 2 (IL1RAPL2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL1RAPL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL1RAPL2 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-IL-18R Polyclonal Antibody

Specificity: IL-18R Polyclonal Antibody detects endogenous levels of IL-18R protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human IL-18R

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IL1RAPL2

Target: IL1RAPL2 (Interleukin 1 Receptor Accessory Protein-Like 2 (IL1RAPL2))

Alternative Name: IL-18R

Background: IL18R1, IL1RRP, Interleukin-18 receptor 1, IL-18R-1, IL-18R1, CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, IL-1Rrp, IL1R-rp, CD218aInterleukin-18 receptor 1 encoded by IL18R1 is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 63kD

Gene ID: 8809

UniProt: Q13478