IL17 Receptor B antibody (AA 251-300)

Catalog No. ABIN7226880

The Rabbit Polyclonal anti-IL17 Receptor B antibody is suitable to detect IL17 Receptor B in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for IL17 Receptor B antibody (AA 251-300) (ABIN7226880)

Target: IL17 Receptor B (IL17RB) (Interleukin 17 Receptor B (IL17RB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17 Receptor B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL17 Receptor B Antibody

Binding Specificity: AA 251-300

Purpose: Rabbit Anti-IL-17RB Polyclonal Antibody

Specificity: IL-17RB Polyclonal Antibody detects endogenous levels of IL-17RB.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from IL-17RB at AA range: 251-300

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IL17 Receptor B

Target: IL17 Receptor B (IL17RB) (Interleukin 17 Receptor B (IL17RB))

Alternative Name: IL-17RB

Background: Interleukin-17 receptor B, IL-17 receptor B, IL-17RB, Cytokine receptor-like 4, IL-17 receptor homolog 1, IL-17Rh1, IL17Rh1, Interleukin-17B receptor, IL-17B receptorThe protein encoded by IL17RB (interleukin 17 receptor B) is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of IL17RB was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.

Molecular Weight: 55kD

Gene ID: 55540

UniProt: Q9NRM6