IL17D antibody (AA 141-190)

Catalog No. ABIN7229098

The Rabbit Polyclonal anti-IL17D antibody (ABIN7229098) specifically detects IL17D in ELISA, IHC and IF. The antibody is reactive with Human samples.

Quick Overview for IL17D antibody (AA 141-190) (ABIN7229098)

Target: IL17D (Interleukin 17D (IL17D))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17D antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-IL17D Antibody

Binding Specificity: AA 141-190

Purpose: Rabbit Anti-IL-17D Polyclonal Antibody

Specificity: The antibody detects endogenous levels of IL-17D

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human IL-17D protein at AA range: 141-190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IL17D

Target: IL17D (Interleukin 17D (IL17D))

Alternative Name: IL-17D

Background: Interleukin-17D, IL-17D, Interleukin-27, IL-27IL17D (Interleukin 17D) is a Protein Coding gene. Among its related pathways are Jak-STAT signaling pathway (KEGG) and IL-17 Family Signaling Pathways. The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent.

Gene ID: 53342

UniProt: Q8TAD2

Pathways: Cellular Response to Molecule of Bacterial Origin