IL17F antibody (AA 81-130)

Catalog No. ABIN7229100

This Rabbit Polyclonal antibody specifically detects IL17F in ELISA, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for IL17F antibody (AA 81-130) (ABIN7229100)

Target: IL17F (Interleukin 17F (IL17F))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17F antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-IL17F Antibody

Binding Specificity: AA 81-130

Purpose: Rabbit Anti-IL-17F Polyclonal Antibody

Specificity: The antibody detects endogenous levels of IL-17F

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human IL-17F protein at AA range: 81-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IL17F

Target: IL17F (Interleukin 17F (IL17F))

Alternative Name: IL-17F

Background: Interleukin-17F, IL-17F, Cytokine ML-1, Interleukin-24, IL-24The protein encoded by IL17F is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. IL17F (Interleukin 17F) is a Protein Coding gene. Diseases associated with IL17F include Candidiasis, Familial, 6, Autosomal Dominant and Chronic Mucocutaneous Candidiasis. Among its related pathways are Cytokine production by Th17 cells in CF (Mouse model) and Th17 Differentiation Pathway.

Gene ID: 112744

UniProt: Q96PD4

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity