IL31RA antibody (Internal Region)

Catalog No. ABIN7217734

This Rabbit Polyclonal antibody specifically detects IL31RA in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for IL31RA antibody (Internal Region) (ABIN7217734)

Target: IL31RA (Interleukin 31 Receptor A (IL31RA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL31RA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL31RA Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-IL-31Rα Polyclonal Antibody

Specificity: IL-31Rα Polyclonal Antibody detects endogenous levels of IL-31Rα protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human IL-31Ralpha

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IL31RA

Target: IL31RA (Interleukin 31 Receptor A (IL31RA))

Alternative Name: IL-31Ralpha

Background: IL31RA, CRL3, GPL, Interleukin-31 receptor subunit alpha, IL-31 receptor subunit alpha, IL-31R subunit alpha, IL-31R-alpha, IL-31RA, Cytokine receptor-like 3, GLM-R, hGLM-R, Gp130-like monocyte receptor, Gp130-like receptor, ZcytoR17Interleukin-31 receptor subunit alpha encoded by IL31RA belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Molecular Weight: 82kD

Gene ID: 133396

UniProt: Q8NI17