IL7R antibody (pTyr449)

Catalog No. ABIN7221780

The Rabbit Polyclonal anti-IL7R antibody (ABIN7221780) specifically detects IL7R in WB, ELISA and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for IL7R antibody (pTyr449) (ABIN7221780)

Target: IL7R (Interleukin 7 Receptor (IL7R))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL7R antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-IL7R Antibody

Binding Specificity: pTyr449

Purpose: IL-7R (phospho Tyr449) Polyclonal Antibody

Specificity: Phospho-IL-7R (Y449) Polyclonal Antibody detects endogenous levels of IL-7R protein only when phosphorylated at Y449.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human IL-7R Phospho-Tyr449

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for IL7R

Target: IL7R (Interleukin 7 Receptor (IL7R))

Alternative Name: IL-7R

Background: Rabbit Anti-IL-7R (phospho Tyr449) Polyclonal Antibody,IL7R, Interleukin-7 receptor subunit alpha, IL-7 receptor subunit alpha, IL-7R subunit alpha, IL-7R-alpha, IL-7RA, CDw127, CD antigen CD127,The protein encoded by IL7R is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found.,Interleukin-7 receptor subunit alpha

Molecular Weight: observerd band 60kDa

Gene ID: 3575

UniProt: P16871

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size