IL9 Receptor antibody (Internal Region)

Catalog No. ABIN7218716

This Rabbit Polyclonal antibody specifically detects IL9 Receptor in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for IL9 Receptor antibody (Internal Region) (ABIN7218716)

Target: IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL9 Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL9 Receptor Antibody

Binding Specificity: Internal Region

Purpose: IL-9R Polyclonal Antibody

Specificity: IL-9R Polyclonal Antibody detects endogenous levels of IL-9R protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human IL-9R

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for IL9 Receptor

Target: IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

Alternative Name: IL-9R

Background: Rabbit Anti-IL-9R Polyclonal Antibody,IL9R, Interleukin-9 receptor, IL-9 receptor, IL-9R, CD129,The interleukin 9 receptor encoded by IL9R is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene.,Interleukin-9 receptor

Molecular Weight: observerd band 58kDa

Gene ID: 3581

UniProt: Q01113

Pathways: JAK-STAT Signaling, Growth Factor Binding