IRAK2 antibody (Internal Region)

Catalog No. ABIN7215476

This Rabbit Polyclonal antibody specifically detects IRAK2 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for IRAK2 antibody (Internal Region) (ABIN7215476)

Target: IRAK2 (Interleukin-1 Receptor-Associated Kinase 2 (IRAK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRAK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IRAK2 Antibody

Binding Specificity: Internal Region

Purpose: IRAK-2 Polyclonal Antibody

Specificity: IRAK-2 Polyclonal Antibody detects endogenous levels of IRAK-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human IRAK-2

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for IRAK2

Target: IRAK2 (Interleukin-1 Receptor-Associated Kinase 2 (IRAK2))

Alternative Name: IRAK-2

Background: Rabbit Anti-IRAK-2 Polyclonal Antibody,IRAK2, Interleukin-1 receptor-associated kinase-like 2, IRAK-2,IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB.,Interleukin-1 receptor-associated kinase-like 2

Molecular Weight: observerd band 70kDa

Gene ID: 3656

UniProt: O43187

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades