ICK antibody

Catalog No. ABIN7220560

The Rabbit Polyclonal anti-ICK antibody (ABIN7220560) specifically detects ICK in WB, ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ICK antibody (ABIN7220560)

Target: ICK (Intestinal Cell (MAK-Like) Kinase (ICK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICK antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ICK Antibody

Purpose: Rabbit Anti-Intestinal Cell Kinase Polyclonal Antibody

Specificity: Intestinal Cell Kinase Polyclonal Antibody detects endogenous levels of Intestinal Cell Kinase protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Intestinal Cell Kinase around the non-phosphorylation site of Y159

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ICK

Target: ICK (Intestinal Cell (MAK-Like) Kinase (ICK))

Alternative Name: Intestinal Cell Kinase

Background: ICK, KIAA0936, Serine/threonine-protein kinase ICK, Intestinal cell kinase, hICK, Laryngeal cancer kinase 2, LCK2, MAK-related kinase, MRKEukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. ICK encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The intestinal cell kinase localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified.

Molecular Weight: 65kD

Gene ID: 22858

UniProt: Q9UPZ9