IRX1 antibody (AA 190-270)

Catalog No. ABIN7225052

The Rabbit Polyclonal anti-IRX1 antibody (ABIN7225052) specifically detects IRX1 in WB, ELISA, IHC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for IRX1 antibody (AA 190-270) (ABIN7225052)

Target: IRX1 (Iroquois Homeobox Protein 1 (IRX1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-IRX1 Antibody

Binding Specificity: AA 190-270

Purpose: Rabbit Anti-IRX1 Polyclonal Antibody

Specificity: IRX1 Polyclonal Antibody detects endogenous levels of IRX1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human IRX1 at AA range: 190-270

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IRX1

Target: IRX1 (Iroquois Homeobox Protein 1 (IRX1))

Alternative Name: IRX1

Background: IRX1, IRXA1, Iroquois-class homeodomain protein IRX-1, Homeodomain protein IRXA1, Iroquois homeobox protein 1IRX1 (iroquois homeobox 1) encodes a member of the Iroquois homeobox protein family. Homeobox genes in this family are involved in pattern formation in the embryo. The gene product has been identified as a tumor suppressor in gastric (PMID: 21602894, 20440264) and head and neck cancers (PMID: 18559491). A pseudogene of IRX1 is located on chromosome 13.

Molecular Weight: 47kD

Gene ID: 79192

UniProt: P78414

Pathways: Tube Formation