IARS2 antibody (AA 40-120)

Catalog No. ABIN7215372

The Rabbit Polyclonal anti-IARS2 antibody (ABIN7215372) specifically detects IARS2 in WB, IHC, IF and ELISA. The antibody is reactive with Human, Mouse and Monkey samples.

Quick Overview for IARS2 antibody (AA 40-120) (ABIN7215372)

Target: IARS2 (Isoleucyl-tRNA Synthetase 2, Mitochondrial (IARS2))

Reactivity: Human, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IARS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Product Details anti-IARS2 Antibody

Binding Specificity: AA 40-120

Purpose: Rabbit Anti-IARS2 Polyclonal Antibody

Specificity: IARS2 Polyclonal Antibody detects endogenous levels of IARS2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human IARS2 at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IARS2

Target: IARS2 (Isoleucyl-tRNA Synthetase 2, Mitochondrial (IARS2))

Alternative Name: IARS2

Background: IARS2, Isoleucine--tRNA ligase, mitochondrial, Isoleucyl-tRNA synthetase, IleRSAminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of isoleucine-tRNA synthetase exist, a cytoplasmic form and a mitochondrial form. IARS2 encodes the mitochondrial isoleucine-tRNA synthetase which belongs to the class-I aminoacyl-tRNA synthetase family.

Molecular Weight: 114kD

Gene ID: 55699

UniProt: Q9NSE4