Junctophilin 2 antibody (AA 611-660)

Catalog No. ABIN7229216

The Rabbit Polyclonal anti-Junctophilin 2 antibody (ABIN7229216) specifically detects Junctophilin 2 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Junctophilin 2 antibody (AA 611-660) (ABIN7229216)

Target: Junctophilin 2 (JPH2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Junctophilin 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Junctophilin 2 Antibody

Binding Specificity: AA 611-660

Purpose: Rabbit Anti-JPH2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of JPH2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human JPH2 protein at AA range: 611-660

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Junctophilin 2

Target: Junctophilin 2 (JPH2)

Alternative Name: JPH2

Background: Junctophilin-2, JP-2, Junctophilin type 2Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by JPH2 is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. JPH2 is a member of the junctophilin gene family. Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described.

Molecular Weight: 76kD

Gene ID: 57158

UniProt: Q9BR39