CDH6 antibody (AA 180-260)

Catalog No. ABIN7217772

This Rabbit Polyclonal antibody specifically detects CDH6 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for CDH6 antibody (AA 180-260) (ABIN7217772)

Target: CDH6 (K-Cadherin (CDH6))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDH6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CDH6 Antibody

Binding Specificity: AA 180-260

Purpose: Rabbit Anti-K-cadherin Polyclonal Antibody

Specificity: K-cadherin Polyclonal Antibody detects endogenous levels of K-cadherin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human K-cadherin at AA range: 180-260

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CDH6

Target: CDH6 (K-Cadherin (CDH6))

Alternative Name: K-cadherin

Background: CDH6, Cadherin-6, Kidney cadherin, K-cadherinCDH6 encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The cadherin 6 is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis.

Molecular Weight: 88kD

Gene ID: 1004

UniProt: P55285

Pathways: Cell-Cell Junction Organization