KAT5 antibody

Catalog No. ABIN7231820

The Rabbit Polyclonal anti-KAT5 antibody is suitable to detect KAT5 in samples from Human, Mouse and Rat. It has been validated for WB and IHC.

Quick Overview for KAT5 antibody (ABIN7231820)

Target: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KAT5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-KAT5 Antibody

Purpose: Rabbit Anti-Tip60 Polyclonal Antibody

Specificity: This antibody detects endogenous levels of Tip60.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human Tip60 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for KAT5

Target: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Alternative Name: Tip60

Background: Histone acetyltransferase KAT5, 60 kDa Tat-interactive protein, Tip60, Histone acetyltransferase HTATIP, HIV-1 Tat interactive protein, Lysine acetyltransferase 5, cPLA(2-interacting proteinThe protein encoded by KAT5 ebelongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of KAT5 results in multiple transcript variants.

Molecular Weight: 60kD

Gene ID: 10524

UniProt: Q92993

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway